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Endocrine Abstracts

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ea0022p626 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Longitudinal combined evaluation of antipituitary antibody titer and immunofluorescence pattern is a suitable tool in predicting autoimmune hypophysitis in patients with autoimmune polyendocrine syndromes

Pane Elena , Rotondi Mario , Colella Caterina , Iacovo Assunta Dello , Mora Liliana Dalla , Bellastella Giuseppe , Sinisi Antonio Agostino , Bizzarro Antonio , Chiovato Luca , Bellastella Antonio , De Bellis Annamaria

Antipituitary antibodies (APA) are frequently present in patients with autoimmune polyendocrine syndrome (APS) but their role in predicting autoimmune hypophysitis (LYH) is still discussed.To evaluate the predictive value of APA investigated by immunofluorescence for the occurrence of pituitary autoimmune dysfunction when considering together some methodological characteristics as immunostaining pattern and antibody titers, we studied 149 APA positive an...
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ea0020p22 | Adrenal | ECE2009

Role of chemokines MIP1α and MIP1β in patients with Addison's disease isolated or associated to autoimmune thyroid disease

De Bellis Annamaria , Pane Elena , Battaglia Marina , Ruocco Giuseppe , Tirelli Gilda , Bellastella Giuseppe , Agostino Sinisi Antonio , Susan Costantini , Capone Francesca , Aiello Talamanca Annarita , Calemma Rosa , Bizzarro Antonio , Bellastella Antonio

High levels of macrophage inflammatory proteins (MIP1α and MIP1β), related to the recruitment of Th1 and Th2 cells, respectively, have been evidenced in some organ and non organ-specific autoimmune diseases. CXCL10/IP10 has been evidenced in patients with autoimmune thyroid disease (ATD) and in Addison’s disease (AD); MIP1α and MIP1β chemokines have not been so far evaluated in these diseases.Aim: To evaluate plasmatic levels MIP...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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